Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.
نویسندگان
چکیده
منابع مشابه
Inhibition of NR2B-Containing N-methyl-D-Aspartate Receptors (NMDARs) in Experimental Autoimmune Encephalomyelitis, a Model of Multiple Sclerosis
Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been suggested for neuroprotection, but selective antagonisation of the NR2B subtype of these receptors, a subtype believed to play a more pivotal ...
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عنوان ژورنال:
- Pharmacological reviews
دوره 50 4 شماره
صفحات -
تاریخ انتشار 1998